SDS-PAGE Analysis Purified GPI Mouse Monoclonal Antibody (CPTC-GPI-1). Confirmation of Purity and Integrity of Antibody.
Immunofluorescence Analysis of human MCF-7 cells labeling GPI with GPI Mouse Monoclonal Antibody (CPTC-GPI-1) followed by Goat anti-Mouse IgG-CF488 (Green). The nuclear counterstain is Reddot (Red)
Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with GPI Mouse Monoclonal Antibody (CPTC-GPI-1).
Western Blot Analysis of T47D, PC3, HePG2 cell lysates using GPI Mouse Monoclonal Antibody (CPTC-GPI-1).
Analysis of Protein Array containing more than 19,000 full-length human proteins using Glucose 6-Phosphate Isomerase Monoclonal Antibody (CPTC-GPI-1).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. Defects in GPI are the cause of hemolytic anemia non-spherocytic due to glucose phosphate isomerase deficiency.