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Home >> Antibodies >> FGF21 (Fibroblast growth factor 21)

FGF21 (Fibroblast growth factor 21)

Mouse Monoclonal Antibody [Clone FGF21/3691]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
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SDS-PAGE Analysis Purified FGF21 Mouse Monoclonal antibody (FGF21/3691). Confirmation of Purity and Integrity of Antibody.

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Formalin-fixed, paraffin-embedded human breast stained with FGF21 Mouse Monoclonal antibody (FGF21/3691).

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Formalin-fixed, paraffin-embedded human kidney stained with FGF21 Mouse Monoclonal antibody (FGF21/3691).

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Analysis of Protein Array containing more than 19,000 full-length human proteins using FGF21 Mouse Monoclonal antibody (FGF21/3691).

Product Details

Synonyms

FGFL; PRO10196

Positive Control

Human kidney or breast cancer.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant fragment (around aa 91-209) of human FGF21 protein (exact sequence is proprietary)

Cellular Localization

Secreted (extracellular)

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2b, kappa

Mol. Weight of Antigen

22kDa

Specificity & Comments

Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10-FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family including four tyrosine kinases, designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Moore, R., et al. 1986. Sequence, topography and protein coding potential of mouse int-2: a putative oncogene activated by mouse mammary tumor virus. EMBO J. 5: 919-924.

Bioinformatics

  •  Entrez Gene ID: 26291
  •  Gene Symbol: FGF21
  •  SwissProt: Q9NSA1
  •  Chromosome Location: 19q13.33
  •  Unigene: 283015