Western Blot of MCF-7 cell lysate using Estrogen Receptor alpha Mouse Monoclonal Antibody (ER505).
SDS-PAGE Analysis Purified Estrogen Receptor alpha Mouse Monoclonal Antibody (ER505). Confirmation of Integrity and Purity of Antibody.
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This MAb is excellent for staining of formalin-fixed, paraffin-embedded breast carcinomas.