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Home >> Antibodies >> Estrogen Receptor (Marker of Estrogen Dependence)

Estrogen Receptor (Marker of Estrogen Dependence)

Mouse Monoclonal Antibody [Clone ER505]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
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Western Blot of MCF-7 cell lysate using Estrogen Receptor alpha Mouse Monoclonal Antibody (ER505).

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SDS-PAGE Analysis Purified Estrogen Receptor alpha Mouse Monoclonal Antibody (ER505). Confirmation of Integrity and Purity of Antibody.

Product Details

Synonyms

Estrogen Receptor alpha delta 4*5,6,7*/654 isoform; Estrogen Receptor alpha delta 4 +49 isoform; Nuclear receptor subfamily 3 group A member 1

Positive Control

MCF-7 cell lysate.

Known Applications & Suggested Dilutions

Western Blot         More Details

Western Blot (1-2ug/ml for 2 hours at Room Temp)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human Estrogen Receptor alpha protein (aa2-185)

Cellular Localization

Nuclear

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

~67kDa

Specificity & Comments

This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This MAb is excellent for staining of formalin-fixed, paraffin-embedded breast carcinomas.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Zafrani B, et. al. Histopathology 2000; 37(6), 536-545.
  2. Harvey JM, et. al. Journal of Clinical Oncology 1999; 17(5), 1474-1481.

Bioinformatics

  •  Entrez Gene ID: 2099
  •  Gene Symbol: ESR1
  •  SwissProt: P03372
  •  Chromosome Location: 6q25.1
  •  Unigene: 208124
NBT00505