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Home >> Antibodies >> DDX41

DDX41

Mouse Monoclonal Antibody [Clone PCRP-DDX41-1B4]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
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Immunofluorescent analysis of PFA-fixed MCF-7 cells. DDX41 Mouse Monoclonal Antibody (PCRP-DDX41-1B4) followed by goat anti-mouse IgG-CF488 (green); counterstain is phalloidin (red).

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Flow cytometric analysis of PFA-fixed HeLa cells. DDX41 Mouse Monoclonal Antibody (PCRP-DDX41-1B4) followed by goat anti-mouse IgG-CF488 (blue), unstained cells (red).

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SDS-PAGE Analysis Purified DDX41 Mouse Monoclonal Antibody (PCRP-DDX41-1B4). Confirmation of Purity and Integrity of Antibody.

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Analysis of Protein Array containing more than 19,000 full-length human proteins using DDX41 Mouse Monoclonal Antibody (PCRP-DDX41-1B4).

Product Details

Synonyms

DEAD (Asp-Glu-Ala-Asp) box polypeptide 41; DEAD box protein 41; DEAD box protein abstrakt homolog; EC 3.6.1.-; Probable ATP-dependent RNA helicase DDX41; Putative RNA helicase; wu:fb92e02; zgc:55896

Positive Control

HeLa or MCF-7 cells.

Known Applications & Suggested Dilutions

Flow Cyt, Western Blot, IF         More Details

Flow Cytometry (1-2ug/million cells)
Western Blot (1-2ug/ml)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human DDX41 protein

Cellular Localization

Nucleus.

Species Reactivity

Human. Predicted to work in Mouse and Rat.

Host / Ig Isotype

Mouse / IgG2b

Mol. Weight of Antigen

69.84kDa

Specificity & Comments

DDX41 (Probable ATP-dependent RNA helicase DDX41, DEAD box protein abstrakt homolog) is a 622 amino acid protein encoded by the human gene DDX41. DDX41 belongs to the DEAD box helicase family (DDX41 subfamily) and contains one CCHC-type zinc finger, one helicase ATP-binding domain and one helicase C-terminal domain. DDX41 is required during post-transcriptional gene expression and is thought to be involved in pre-mRNA splicing. DDX41 is believed to be a probable ATP-dependent RNA helicase. RNA helicases are highly conserved enzymes that utilize the energy derived from NTP hydrolysis to modulate the structure of RNA. RNA helicases participate in all biological processes that involve RNA, including transcription, splicing and translation.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Irion, U. and Leptin, M. 2000. Curr. Biol. 9: 1373-1381.
  2. Nucleic Acids Res. 38:D142-D148 (2010).

Bioinformatics

  •  Entrez Gene ID: 51428
  •  Gene Symbol: DDX41
  •  SwissProt: Q9UJV9
  •  Chromosome Location: 5q35.3
  •  Unigene: 484288