Immunofluorescent analysis of PFA-fixed MCF-7 cells. DDX41 Mouse Monoclonal Antibody (PCRP-DDX41-1B4) followed by goat anti-mouse IgG-CF488 (green); counterstain is phalloidin (red).
Flow cytometric analysis of PFA-fixed HeLa cells. DDX41 Mouse Monoclonal Antibody (PCRP-DDX41-1B4) followed by goat anti-mouse IgG-CF488 (blue), unstained cells (red).
SDS-PAGE Analysis Purified DDX41 Mouse Monoclonal Antibody (PCRP-DDX41-1B4). Confirmation of Purity and Integrity of Antibody.
Analysis of Protein Array containing more than 19,000 full-length human proteins using DDX41 Mouse Monoclonal Antibody (PCRP-DDX41-1B4).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
DDX41 (Probable ATP-dependent RNA helicase DDX41, DEAD box protein abstrakt homolog) is a 622 amino acid protein encoded by the human gene DDX41. DDX41 belongs to the DEAD box helicase family (DDX41 subfamily) and contains one CCHC-type zinc finger, one helicase ATP-binding domain and one helicase C-terminal domain. DDX41 is required during post-transcriptional gene expression and is thought to be involved in pre-mRNA splicing. DDX41 is believed to be a probable ATP-dependent RNA helicase. RNA helicases are highly conserved enzymes that utilize the energy derived from NTP hydrolysis to modulate the structure of RNA. RNA helicases participate in all biological processes that involve RNA, including transcription, splicing and translation.