SDS-PAGE Analysis Purified Cytokeratin 10/13 Mouse Monoclonal Antibody (DE-K13). Confirmation of Purity and Integrity of Antibody.
Formalin-fixed; paraffin-embedded human tonsil stained with Cytokeratin 10/13 Mouse Monoclonal Antibody (DE-K13).
Immunofluorescent analysis of MeOH-fixed MCF-7 cells using Cytokeratin 10/13 Mouse Monoclonal Antibody (DE-K13) followed by goat anti-mouse IgG-CF488. Nuclei counterstained with RedDot.
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
This antibody recognizes cytokeratin 10 (56.5kDa) and cytokeratin 13 (53kDa) in Western blotting. It recognizes only cytokeratin 13 in formalin-fixed, paraffin-embedded tissue sections. It does not react with cytokeratin 10 positive, cytokeratin 13 negative epithelia such as epidermis. However, on frozen sections this MAb serves as differentiation-related marker of all stratified epithelia; it stains all suprabasal cells in both cornifying and non-cornifying stratified epithelia and more differentiated cells of squamous carcinomas.