2 Union Square, Union City, CA 94587
contact@NeoBiotechnologies.com
510-376-5603

Home >> Antibodies >> CTBP2 (C-terminal binding protein 2)

CTBP2 (C-terminal binding protein 2)

Mouse Monoclonal Antibody [Clone PCRP-CTBP2-1A9]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
img

Flow Cytometric Analysis of PFA-fixed HeLa cells. CTBP2 Mouse Monoclonal Antibody (PCRP-CTBP2-1A9) followed by goat anti-mouse IgG-CF488 (blue); unstained cells (red).

img

Immunofluorescence Analysis of HeLa cells using CTBP2 Mouse Monoclonal Antibody (PCRP-CTBP2-1A9) followed by goat anti-mouse IgG-CF488 (green). CF640A phalloidin (red).

img

SDS-PAGE Analysis Purified CTBP2 Mouse Monoclonal Antibody (PCRP-CTBP2-1A9). Confirmation of Purity and Integrity of Antibody.

img

Analysis of Protein Array containing more than 19,000 full-length human proteins using CTBP2 Mouse Monoclonal Antibody (PCRP-CTBP2-1A9).

Product Details

Synonyms

C-terminal-binding protein 2 (CTBP2); Ribeye

Positive Control

Molt-4 or HeLa cells.

Known Applications & Suggested Dilutions

Flow Cyt, IF         More Details

Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human CTBP2 protein

Cellular Localization

Nucleus. Cell junction > synapse.

Species Reactivity

Human

Host / Ig Isotype

Mouse / IgG2b

Mol. Weight of Antigen

95.2kDa

Specificity & Comments

The gene CTBP2 (C-terminal binding protein 2) encodes a member of the CtBP-family. The gene is mapped to human chromosome 21q21.3. It is found to be expressed ubiquitously, with higher expression in the heart, skeletal muscle, and pancreas. The gene CTBP2 (C-terminal binding protein 2) encodes a protein that functions as a transcriptional co-repressor of several tumor suppressor genes resulting in enhanced cancer cell migration and invasion. Its expression is found to be upregulated in hepatocellular carcinoma (HCC). It may be a potential prognostic marker for post liver resection HCC. It is involved in several types of tumor initiation, progression and response to therapy. It is found to interact with the C-terminal region of adenovirus type 2/5 E1A protein, a region that negatively regulates tumorigenicity and the extent of oncogenic transformation.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Xin Zheng et. al. Oncotarget, 2015 Feb 28;6(6):3752-69.

Bioinformatics

  •  Entrez Gene ID: 1488
  •  Gene Symbol: CTBP2
  •  SwissProt: P56545
  •  Chromosome Location: 21q21.3
  •  Unigene: 501345