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Home >> Antibodies >> Clathrin, Heavy Chain

Clathrin, Heavy Chain

Mouse Monoclonal Antibody [Clone CLTC/1431]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
459.00
459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
459.00
459.00
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SDS-PAGE Analysis of Purified Clathrin HC Mouse Monoclonal Antibody (CLTC/1431). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

Clathrin heavy chain; Clathrin heavy chain 1; Clathrin heavy chain 2; Clathrin heavy chain on chromosome 17 (CHC17 or CHC-17); CLH22; CLTC; CLTCL; CLTCL1; CLTCL2; CLTD

Positive Control

HeLa cells. Placenta or Prostate Carcinoma.

Known Applications & Suggested Dilutions

ELISA         More Details

ELISA (For coating, order Ab without BSA)
Optimal dilution for a specific application should be determined.

Immunogen

Purified recombinant N-terminal fragment of human Clathrin Heavy Chain

Cellular Localization

Cytoplasmic

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

192kDa

Specificity & Comments

Recognizes protein of 192kDa, which is identified as Clathrin Heavy Chain. Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin heavy chain (HC) is composed of a terminal globular domain, a distal segment and a proximal segment containing a light chain-binding site. The proximal segment of the Clathrin HC protein is essential for interactions between Clathrin heavy chains and light chains, which result in the formation of the triskelion structure.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Pearse, B.M. 1987. Clathrin and coated vesicles. EMBO J. 6: 2507-2512.

Bioinformatics

  •  Entrez Gene ID: 1213
  •  Gene Symbol: CLTC
  •  SwissProt: P53675, Q00610
  •  Chromosome Location: 17q23.1
  •  Unigene: 491351
NBT01431