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Home >> Antibodies >> Chromogranin A / CHGA (Neuroendocrine Marker)

Chromogranin A / CHGA (Neuroendocrine Marker)

Mouse Monoclonal Antibody [Clone CHGA/777]

Catalog #


0.5 ml at 100ug/ml

Price (USD)



Purified Ab conjugated to CF488

Catalog No


0.5 ml at 100ug/ml


Purified Ab conjugated to CF488

Price (USD)


Product Details


Beta-Granin; CGA; CHGA; Chromogranin A Parathyroid Secretory Protein 1; ER-37; Pancreastatin; Parastatin; Pituitary Secretory Protein I; SP-I; Vasostatin I or II

Positive Control

PC12 cells. Adrenal gland, bowel, thyroid, pancreas or pheochromocytoma.

Known Applications & Suggested Dilutions

Flow Cyt, IF         More Details

Flow Cytometry (5ul per test per one million cells or 5ul per 100ul of whole blood)
Immunofluorescence (1:50-1:100)
Optimal dilution for a specific application should be determined.


Recombinant human CHGA protein

Cellular Localization

Finely granular cytoplasmic

Species Reactivity


Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen


Specificity & Comments

Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin A.

Related Products

Antibody Purified from Bioreactor Concentrate by Protein A/G and conjugated to various reporter molecules. Prepared in 10mM PBS with 0.05% BSA and 0.05% azide. Contact us if you require this Ab in a different format.

Key References

  1. Schmid, K.W., et al. 1993. Chromogranin A, secretogranin II and vasoactive intestinal peptide in phaeochromocytomas and ganglioneuromas. Histopathology 22: 527-533.


  •  Entrez Gene ID: 1113
  •  Gene Symbol: CHGA
  •  SwissProt: P10645
  •  Chromosome Location: 14q32.12
  •  Unigene: 150793