Home >> Antibodies >> Chromogranin A / CHGA (Neuroendocrine Marker)

Chromogranin A / CHGA (Neuroendocrine Marker)

Recombinant Rabbit Monoclonal Antibody [Clone CHGA/4544R]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

Formalin-fixed, paraffin-embedded human pancreas stained with Chromogranin A Recombinant Rabbit Monoclonal Antibody (CHGA/4544R).

Formalin-fixed, paraffin-embedded human pancreas stained with Chromogranin A Recombinant Rabbit Monoclonal Antibody (CHGA/4544R).

Product Details

Synonyms

Beta-Granin; CGA; CHGA; Chromogranin A Parathyroid Secretory Protein 1; ER-37; Pancreastatin; Parastatin; Pituitary Secretory Protein I; SP-I; Vasostatin I or II

Positive Control

PC12 cells. Adrenal gland, bowel, thyroid, pancreas, or pheochromocytoma.

Known Applications & Suggested Dilutions

IHC-P More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Synthetic peptide corresponding to residues withinaa400 to aa600 of Chromogranin A was used as an immunogen.

Cellular Localization

Cytoplasm

Species Reactivity

Human.

Host / Ig Isotype

Rabbit / IgG

Mol. Weight of Antigen

51kDa

Specificity & Comments

Chromogranin A (CGA) is an acidic protein which is reported to be widely expressed in neural tissues and in secretory granules of human endocrine cells e.g. parathyroid gland, adrenal medulla, anterior pituitary gland, islet cells of the pancreas and C cells of the thyroid. GA is found in the large majority of epithelial NE tumors: pituitary adenomas, parathyroid and pancreatic islet cell tumors, medullary thyroid carcinoma, and carcinoid tumors. Together with synaptophysin, CGA is the most important marker for the identification of NE and neuronal tumors and NE/neuronal differentiation in other tumors.