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Home >> Antibodies >> CD15 / FUT4 (Reed-Sternberg Cell Marker)

CD15 / FUT4 (Reed-Sternberg Cell Marker)

Mouse Monoclonal Antibody [Clone SPM490]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
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Immunofluorescence staining of U937 cells using CD15 Monoclonal Antibody (SPM490) followed by goat anti-Mouse IgG conjugated to CF488 (green). Nuclei are stained with Reddot.

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Formalin-fixed, paraffin-embedded human Hodgkin’s Lymphoma stained with CD15 Monoclonal Antibody (SPM490)

Product Details

Synonyms

3 Fucosyl N Acetyl Lactosamine; Alpha (1,3) Fucosyltransferase; Alpha 13 fucosyltransferase FucT; ELAM Ligand Fucosyltransferase; ELFT; FCT3A; Fuc-TIV; Fucosyltransferase 4 Alpha 1 3 Fucosyltransferase Myeloid Specific; Fucosyltransferase 4; Galactoside 3 L Fucosyltransferase; Lewis X; LeX; SSEA1; Stage Specific Embryonic Antigen 1

Positive Control

U937 cells, Reed-Sternberg's cells in Hodgkin's lymphoma.

Known Applications & Suggested Dilutions

IF, IHC-P         More Details

Immunofluorescence (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)Optimal dilution for a specific application should be determined.

Immunogen

Myelomonocytic leukemia cells

Cellular Localization

Cell surface and granular paranuclear

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgM, kappa

Mol. Weight of Antigen

~220kDa (Glycoprotein)

Specificity & Comments

CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Bettelheim, P., et al., Cluster Report: CD15, in : Knapp, W., et al. (eds), Leucocyte Typing IV, Oxford Univ. Press, pp 798-799.
  2. Hogg, N., et al., Myeloid antigens: new and previously defines clusters, in: McMichae, A.J., et al (eds), Leucocyte Typing III, Oxford Univ. Press, pp 576-602.

Bioinformatics

NBT00504