Home >> Antibodies >> CD137L / 4-1BBL / TNFSF9

CD137L / 4-1BBL / TNFSF9

Biotinylated Mouse Monoclonal Antibody [Clone CD137L/1547]

Printable

Key References

Bioinformatics

Catalog #

Size

0.5 ml at 100ug/ml

Price (USD)

499.00

Formulation

Purified Ab conjugated to Biotin

Performance Guarantee

Catalog No

Size

0.5 ml at 100ug/ml

Formulation

Purified Ab conjugated to Biotin

Price (USD)

499.00

Printable

Key References

Bioinformatics

Formalin-fixed, paraffin-embedded human kidney stained with Biotin-conjugated CD137L Mouse Monoclonal Antibody (CD137L/1547).

Formalin-fixed, paraffin-embedded human kidney stained with Biotin-conjugated CD137L Mouse Monoclonal Antibody (CD137L/1547).

SDS-PAGE Analysis Purified CD137L Mouse Monoclonal Antibody (CD137L/1547) (unconjugated). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human kidney stained with Biotin-conjugated CD137L Mouse Monoclonal Antibody (CD137L/1547).

SDS-PAGE Analysis Purified CD137L Mouse Monoclonal Antibody (CD137L/1547) (unconjugated). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

4-1BB ligand; 4-1BBL; CD137L; ILA ligand (TNF related); Ly63l; Tumor necrosis factor ligand 5A (TNLG5A); Tumor necrosis factor ligand superfamily member 9 (TNFSF9)

Positive Control

Raji, 293T or HEK293 cells. Human renal cell carcinoma or lung carcinoma.

Known Applications & Suggested Dilutions

Flow Cyt, IF, IHC-P More Details

Flow Cytometry (2-4ug/million cells in 0.1ml)
Immunofluorescence (2-4ug/ml)
Immunohistochemistry (Formalin-fixed) (2-4ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °
C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human CD137L protein

Cellular Localization

Cell Surface and Cytoplasmic

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2a, kappa

Mol. Weight of Antigen

27kDa

Specificity & Comments

TNFSF9 / 4-1BBL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9 / 4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9 / 4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. It has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine is required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.