2 Union Square, Union City, CA 94587
contact@NeoBiotechnologies.com
510-376-5603

Home >> Antibodies >> Adiponectin (Marker of Obesity)

Adiponectin (Marker of Obesity)

Mouse Monoclonal Antibody [Clone ADPN/1370]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
img

Formalin-fixed, paraffin-embedded human Kidney stained with Adiponectin Mouse Monoclonal Antibody (ADPN/1370).

img

Western blot Analysis of human Kidney lysate using Adiponectin Mouse Monoclonal Antibody (ADPN/1370).

img

SDS-PAGE Analysis Purified Adiponectin Mouse Monoclonal Antibody (ADPN/1370). Confirmation of Integrity and Purity of Antibody.

img

Analysis of Protein Array containing more than 19,000 full-length human proteins using Adiponectin Mouse Monoclonal Antibody (ADPN/1370).

Product Details

Synonyms

Adiponectin; Adipocyte complement-related 30kDa protein (ACRP30); Adipocyte-specific secretory protein; Adiponectin, C1Q and collagen domain containing (ACDC); ADIPOQ; Adipose most abundant gene transcript 1 protein; Adipose specific collagen like factor; ADIPQTL1; ADPN; APM-1; Gelatin-binding protein 28 (GBP28)

Positive Control

HeLa cells. Kidney.

Known Applications & Suggested Dilutions

Western Blot, IHC-P         More Details

Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human Adiponectin protein fragment (around aa 145-226) (exact sequence is proprietary)

Cellular Localization

Cytoplasmic & Cell Surface

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2b, kappa

Mol. Weight of Antigen

26-30kDa

Specificity & Comments

This MAb reacts with adiponectin, an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Dos Santos, E., et al. 2008. Adiponectin mediates an antiproliferative response in human MDA-MB 231 breast cancer cells. Oncol. Rep. 20: 971-977.

Bioinformatics

  •  Entrez Gene ID: 9370
  •  Gene Symbol: ADIPOQ
  •  SwissProt: Q15848
  •  Chromosome Location: 3q27
  •  Unigene: 80485
NBT01370