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Home >> Antibodies >> Adiponectin (Marker of Obesity)
Adiponectin (Marker of Obesity)

Mouse Monoclonal Antibody [Clone ADPN/1370]

Catalog #
Size
20 ug
100 ug
100 ug
Price (USD)
199.00
429.00
429.00
Formulation
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Catalog No
Size
20 ug
100 ug
100 ug
Formulation
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Price (USD)
199.00
429.00
429.00
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Formalin-fixed, paraffin-embedded human Kidney stained with Adiponectin Mouse Monoclonal Antibody (ADPN/1370).

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Western blot Analysis of human Kidney lysate using Adiponectin Mouse Monoclonal Antibody (ADPN/1370).

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SDS-PAGE Analysis Purified Adiponectin Mouse Monoclonal Antibody (ADPN/1370) Confirmation of Integrity and Purity of Antibody

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Analysis of Protein Array containing more than 19,000 full-length human proteins using Adiponectin Mouse Monoclonal Antibody (ADPN/1370).

Product Details

Synonyms

Adiponectin; Adipocyte complement-related 30kDa protein (ACRP30); Adipocyte-specific secretory protein; Adiponectin, C1Q and collagen domain containing (ACDC); ADIPOQ; Adipose most abundant gene transcript 1 protein; Adipose specific collagen like factor; ADIPQTL1; ADPN; APM-1; Gelatin-binding protein 28 (GBP28)

Positive Control

HeLa cells. Kidney

Known Applications & Suggested Dilutions

ELISA, IF, IHC-P         More Details
ELISA (For coating, use antibody without BSA),Flow Cytometry (0.5-1ug/million cells)
Immunofluorescence (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human Adiponectin protein fragment

Cellular Localization

Cytoplasmic & Cell Surface

Species Reactivity

Human. Others not known.

Host / Ig Isotype

Mouse / IgG2b, kappa

Specificity & Comments

This MAb reacts with adiponectin, an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism.

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200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Dos Santos, E., et al. 2008. Adiponectin mediates an antiproliferative response in human MDA-MB 231 breast cancer cells. Oncol. Rep. 20: 971-977.

Bioinformatics

  •  Entrez Gene ID: 9370
  •  Gene Symbol: ADIPOQ
  •  SwissProt: Q15848
  •  Chromosome Location: 3q27
  •  Unigene: 80485
DOC#01370