TADA1 (Transcriptional Adapter 1) / STAF42 [PCRP-TADA1-1C9]
TAF42 (SPT3-associated factor 42), also known as TADA1 (transcriptional adapter 1), ADA1, HFI1 or hADA1, is a 335 amino acid nuclear protein that belongs to the TADA1 family. As a component of the STAGA transcription coactivator-HAT complex, STAF42 is most likely involved in transcriptional regulation. The gene that encodes STAF42 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
- Probably involved in transcriptional regulation.
Known Applications & Suggested Dilutions
- Immunoprecipitation (1-2ug per 100-500ug of total protein)
- Western Blot (1-2ug/ml)
- ,Flow Cytometry (1-2ug/million cells)
- ,Optimal dilution for a specific application should be determined.
- Sutcliffe EG, et al. Cancer Genet, 2020 Aug. PMID 32805687
Storage & Stability
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
This antibody is available for research use only and is not approved for use in diagnosis.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.