Formalin-fixed, paraffin-embedded human Placenta stained with TIMP2 Mouse Monoclonal Antibody (TIMP2/2044).
SDS-PAGE Analysis Purified TIMP2 Mouse Monoclonal Antibody (TIMP2/2044). Confirmation of Purity and Integrity of Antibody.
Analysis of Protein Array containing more than 19,000 full-length human proteins using TIMP2 Mouse Monoclonal Antibody (TIMP2/2044)
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.