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Home >> Antibodies >> SOX9 / SRY-box 9

SOX9 / SRY-box 9

Recombinant Rabbit Monoclonal Antibody [Clone SOX9/3141R]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
459.00
459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
459.00
459.00
img

Formalin-fixed, paraffin-embedded human Pancreas stained with SOX9 Recombinant Rabbit Monoclonal Antibody (SOX9/3141R).

img

SDS-PAGE Analysis Purified SOX9 Recombinant Rabbit Monoclonal Antibody (SOX9/3141R). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

Campomelic Dysplasia Autosomal Sex Reversal (CMD1); SRA1; SRXX2; SRY (sex determining region Y) box 9; SRY related HMG box gene 9; Transcription factor SOX9

Positive Control

HepG2 cells. Pancreas.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human SOX9 protein fragment (around aa 393-508) (exact sequence is proprietary)

Cellular Localization

Nuclear

Species Reactivity

Human.

Host / Ig Isotype

Rabbit / IgG

Mol. Weight of Antigen

65kDa

Specificity & Comments

Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Zhu, H., et al. 2013. Upregulation of SOX9 in osteosarcoma and its association with tumor progression and patients prognosis. Diagn.Pathol. 8:183.

Bioinformatics

  •  Entrez Gene ID: 6662
  •  Gene Symbol: SOX9
  •  SwissProt: P48436
  •  Chromosome Location: 17q24.3
  •  Unigene: 647409
NBT03141