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Home >> Antibodies >> Ki-67 (Proliferating Cell Marker)

Ki-67 (Proliferating Cell Marker)

Biotinylated Mouse Monoclonal Antibody [Clone MKI67/2465]

Catalog #


0.5 ml at 100ug/ml

Price (USD)



Purified Ab conjugated to Biotin

Catalog No


0.5 ml at 100ug/ml


Purified Ab conjugated to Biotin

Price (USD)


Formalin-fixed, paraffin-embedded human tonsil stained with Biotin-conjugated Ki67 Mouse Monoclonal Antibody (MKI67/2465).


SDS-PAGE Analysis Purified Ki67 Mouse Monoclonal Antibody (MKI67/2465) (unconjugated) Confirmation of Purity and Integrity of Antibody.


Analysis of Protein Array containing more than 19,000 full-length human proteins using Ki67-Monospecific Mouse Monoclonal Antibody (MKI67/2465).

Product Details


KI-67; Ki67; KI-67 Antigen (KIA); MKI67; Proliferation related Ki-67 antigen

Positive Control

Any actively proliferating cells. Human skin, tonsil or lymph node.

Known Applications & Suggested Dilutions

Flow Cyt, IF, IHC-P         More Details

Flow Cytometry (5ul per test per million cells)
Immunofluorescence (2-4ug/ml at RT)
Immunohistochemistry (Formalin-fixed) (2-4ug/ml at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.


Recombinant fragment (around aa 2293-2478) of human Ki67 protein (exact sequence is proprietary)

Cellular Localization


Species Reactivity


Host / Ig Isotype

Mouse / IgG2b, kappa

Mol. Weight of Antigen

345kDa and 395kDa

Specificity & Comments

Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations.

Related Products

Antibody purified from Bioreactor Concentrate by Protein A/G and conjugated to Biotin. Prepared in 10mM PBS with 0.05% BSA and 0.05% azide.

Key References

  1. Gerdes J,et al.1984.J. Immunol.133:1710.
  2. Schluter C,et al.1993J. Cell Biol.123:513.


  •  Entrez Gene ID: 4288
  •  Gene Symbol: MKI67
  •  SwissProt: P46013
  •  Chromosome Location: 10q26.2
  •  Unigene: 689823