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Home >> Antibodies >> FOXQ1

FOXQ1

Mouse Monoclonal Antibody [Clone PCRP-FOXQ1-2D2]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
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SDS-PAGE Analysis. Purified FOXQ1 Mouse Monoclonal Antibody (PCRP-FOXQ1-2D2). Confirmation of Purity and Integrity of Antibody.

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Flow cytometric analysis of PFA-fixed HeLa cells. FOXQ1 Mouse Monoclonal Antibody (PCRP-FOXQ1-2D2) followed by goat anti-mouse IgG-CF488 (blue); unstained cells (red).

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Analysis of Protein Array containing more than 19,000 full-length human proteins using FOXQ1 Mouse Monoclonal Antibody (PCRP-FOXQ1-2D2.

Product Details

Synonyms

Forkhead box protein Q1; FOXQ1; Hepatocyte nuclear factor 3 forkhead homolog 1; HFH1; HNF3/forkhead like protein 1; MGC77469; Q1; Winged helix / forkhead transcription factor; zgc:77469

Positive Control

HeLa or K562 cells.

Known Applications & Suggested Dilutions

ELISA, Flow Cyt, Western Blot, IP         More Details

ELISA (For coating, order antibody without BSA)
Flow Cytometry (1-2ug/million cells)
Western Blot (1-2ug/ml)
Immunoprecipitation (1-2ug per 100-500ug of total protein (1ml of cell lysate))
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human FOXQ1 protein

Cellular Localization

Nucleus.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1

Mol. Weight of Antigen

41.5kDa

Specificity & Comments

DNA replication is initiated by the binding of initiation factors to the origin of replication. Nucleosomes inhibit access to the replication machinery at these origin sequences. Nucleosome remodeling factors increase the accessibility of nucleosomal DNA to transcriptional regulators. CHRAC15 and CHRAC17 are subunits of the nucleosomal remodeling factor CHRAC (chromatin accessibility complex), which increases the accessibility of nucleosomal DNA in an ATP-dependent manner. Unlike other known chromatin remodeling factors, CHRAC also functions during chromatin assembly by using ATP to convert irregular chromatin into a regular array of nucleosomes with even spacing. This conversion process occurs when CHRAC organizes randomly deposited histones into a regularly spaced array. In the presence of CHRAC, the nucleosomal ATPase ISWI catalyzes several ATP-dependent transitions of chromatin structure.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Blackshaw S., et al. Nature methods15.5 (2018 May): 330-338.
  2. Nucleic Acids Res. 38:D142-D148 (2010).

Bioinformatics

  •  Entrez Gene ID: 94234
  •  Gene Symbol: FOXQ1
  •  SwissProt: Q9C009
  •  Chromosome Location: 6p25
  •  Unigene: 591352