Home >> Antibodies >> CDX2 / Caudal Type Homeobox 2 (GI Epithelial Marker)

CDX2 / Caudal Type Homeobox 2 (GI Epithelial Marker)

Recombinant Mouse Monoclonal Antibody [Clone rCDX2/6921]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

IHC analysis of formalin-fixed, paraffin-embedded human colon adenocarcinoma. Strong nuclear staining using rCDX2/6921 at 2ug/ml in PBS for 30min RT. Inset: PBS instead of primary, secondary antibody control.

Formalin-fixed, paraffin-embedded human colon carcinoma stained with CDX2 Recombinant Mouse Monoclonal Antibody (rCDX2/6921).

SDS-PAGE Analysis Purified CDX2 Recombinant Mouse Monoclonal Antibody (rCDX2/6921). Confirmation of Purity and Integrity of Antibody.

IHC analysis of formalin-fixed, paraffin-embedded human colon adenocarcinoma. Strong nuclear staining using rCDX2/6921 at 2ug/ml in PBS for 30min RT. Inset: PBS instead of primary, secondary antibody control.

Formalin-fixed, paraffin-embedded human colon carcinoma stained with CDX2 Recombinant Mouse Monoclonal Antibody (rCDX2/6921).

SDS-PAGE Analysis Purified CDX2 Recombinant Mouse Monoclonal Antibody (rCDX2/6921). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

Caudal type homeobox 2; Caudal type homeobox transcription factor 2; Caudal-type homeobox protein 2; CDX2

Positive Control

HT29 cells. Human colon carcinoma

Known Applications & Suggested Dilutions

IHC-P More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant fragments and synthetic peptides from human CDX2 protein (exact sequences are proprietary)

Cellular Localization

Nucleus.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

40kDa

Specificity & Comments

The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids �and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. �However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.