Home >> Antibodies >> CD44v6 (Marker of Tumor Metastasis)

CD44v6 (Marker of Tumor Metastasis)

Mouse Monoclonal Antibody [Clone 2F10]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with CD44v6 Mouse Monoclonal Antibody (2F10).

Formalin-fixed, paraffin-embedded human Cervix Carcinoma stained with CD44v6 Mouse Monoclonal Antibody (2F10).

SDS-PAGE Analysis Purified CD44v6 Mouse Monoclonal Antibody (2F10). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with CD44v6 Mouse Monoclonal Antibody (2F10).

Formalin-fixed, paraffin-embedded human Cervix Carcinoma stained with CD44v6 Mouse Monoclonal Antibody (2F10).

SDS-PAGE Analysis Purified CD44v6 Mouse Monoclonal Antibody (2F10). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

LHR; BA-1; chondroitin sulfate proteoglycan 8 (CSPG8); Epican; Extracellular Matrix Receptor III (ECM III); GP90 Lymphocyte Homing Adhesion Receptor; HCAM; HCELL; hematopoietic cell E- and L-selectin ligand; Heparan Sulfate Proteoglycan; Hermes Antigen; HAS; HUTCH I; Hyaluronate Receptor; Indian blood group; Inlu Related p80 Glycoprotein; Ly 24; MDU2; MDU3; MIC4; MUTCH I; Phagocytic Glycoprotein 1 (PGP-1)

Positive Control

Cervix or Tongue Squamous Cell Carcinoma

Known Applications & Suggested Dilutions

Flow Cyt, IF, Western blotting, Immunohistology More Details

Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Western blotting (1-2ug/ml)
Immunohistology (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant fragment corresponding to the v9 domain of human CD44

Cellular Localization

Cell Surface

Species Reactivity

Human. Others-not tested.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

80-95kDa

Specificity & Comments

This antibody recognizes an epitope encoded by exon v6 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA.The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.