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Adiponectin (Marker of Obesity)

Mouse Monoclonal Antibody [Clone ADPN/4255]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

SDS-PAGE Analysis Purified Adiponectin Mouse Monoclonal Antibody (ADPN/4255) Confirmation of Integrity and Purity of Antibody.

Western blot Analysis of human kidney tissue lysate using Adiponectin Mouse Monoclonal Antibody (ADPN/4255).

SDS-PAGE Analysis Purified Adiponectin Mouse Monoclonal Antibody (ADPN/4255) Confirmation of Integrity and Purity of Antibody.

Western blot Analysis of human kidney tissue lysate using Adiponectin Mouse Monoclonal Antibody (ADPN/4255).

Product Details

Synonyms

Adiponectin; Adipocyte complement-related 30kDa protein (ACRP30); Adipocyte-specific secretory protein; Adiponectin, C1Q and collagen domain containing (ACDC); ADIPOQ; Adipose most abundant gene transcript 1 protein; Adipose specific collagen like factor; ADIPQTL1; ADPN; APM-1; Gelatin-binding protein 28 (GBP28)

Positive Control

HeLa cells. Human kidney.

Known Applications & Suggested Dilutions

ELISA, Western Blot More Details

ELISA (For coating, use antibody without BSA)
Western Blot (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Synthetic peptide corresponding to the globular head region of the Adiponectin molecule.

Cellular Localization

Cytoplasm and cell surface.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1

Mol. Weight of Antigen

26-30kDa

Specificity & Comments

This MAb reacts with adiponectin, an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore, adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism. (Hotta K, et al.) Clone ADPN/4255 is also used in a combination ELISA with clone ADPN/4256, acting as the detection antibody.