Breast Cancer Antibodies

Breast cancer is a multifaceted disease characterized by uncontrolled cell growth in the breast tissue. It encompasses several distinct types, differing in terms of origins and growth patterns. Techniques including Western blots, ELISA, flow cytometry, co-immunoprecipitation, and immunohistochemistry can distinguish among the different types of breast cancer and provide vital information about cell proliferation and disease progression, which is critical for the early detection, prognosis/monitoring, and treatment of the disease.

NeoBiotechnologies is your trusted partner in breast cancer research, offering a comprehensive range of high-quality IHC-validated antibodies targeting breast cancer protein biomarkers (see the table below).

Notable breast cancer biomarkers:

  • Estrogen Receptor (ER): ER-positive breast cancer is characterized by the presence of estrogen receptors on the cancer cells. ER status is crucial for treatment decisions, as patients with ER-positive tumors may benefit from hormone therapy.
  • Progesterone Receptor (PR): PR-positive breast cancer indicates the presence of progesterone receptors on the cancer cells. Similar to ER, hormone therapy may be used in the treatment of PR-positive tumors.
  • Human Epidermal Growth Factor Receptor 2 (HER2): HER2-positive breast cancer has amplification or overexpression of the HER2 gene or protein. HER2 status helps determine treatment options, as targeted therapies like trastuzumab (Herceptin) are used in HER2-positive cases.
  • Ki-67: a protein associated with cell proliferation. Its measurement can provide information about the growth rate of breast cancer cells, which is essential for prognosis and treatment planning.
  • p53: a protein involved in regulating cell growth and DNA repair. Mutations in the p53 gene and aberrant expression of the p53 protein are associated with some forms of breast cancer and can affect prognosis and treatment decisions.
  • Cyclin D1: a protein involved in cell cycle regulation and is often overexpressed in specific breast cancer subtypes, such as luminal breast cancers.
  • Topoisomerase II (Topo II): an enzyme involved in DNA replication and repair. Its expression can impact the responsiveness of breast cancer to specific chemotherapy agents.
  • Epidermal Growth Factor Receptor (EGFR): a cell surface receptor that can be overexpressed in some breast cancer subtypes, and its presence may influence treatment decisions. EGFR expression or overexpression is associated with some breast cancer subtypes and may influence treatment options.
  • Cytokeratins (CK): intermediate filament proteins found in epithelial cells, including breast cancer cells. They are often used in immunohistochemistry to identify and subtype breast cancer cells.
  • BRCA1 and BRCA2: Mutations in the BRCA1 and BRCA2 genes are associated with an increased risk of hereditary breast cancer. Testing for these mutations can help identify individuals at high risk for breast cancer.
  • PTEN (Phosphatase and Tensin Homolog): Loss of PTEN expression is associated with some breast cancers and may be related to treatment response and prognosis.

Breast Cancer

  • In Stock
    Best Seller

    Catenin, beta (p120) Antibody [15B8]

    Price range: $259.00 through $559.00
    Catalog Number:
    1499-MSM3
    Gene:
    CTNNB1
    Application:
    Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
    Reactivity:
    Chicken, Cow, Dog, Human, Mouse, Rat
    Host:
    Mouse
    Isotype:
    IgG1
  • In Stock

    ER-beta (Estrogen Receptor beta-1) Antibody [PPG5/10]

    Price range: $259.00 through $559.00
    Catalog Number:
    2100-MSM10
    Gene:
    ESR2
    Application:
    Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
    Reactivity:
    Horse, Human, Monkey, Mouse, Pig, Rat, Sheep
    Host:
    Mouse
    Isotype:
    IgG2a
  • In Stock

    Estrogen Receptor (Marker of Estrogen Dependence) Antibody [AER311]

    Price range: $259.00 through $559.00
    Catalog Number:
    2099-MSM6
    Gene:
    ESR1
    Application:
    Flow Cytometry, Immunofluorescence
    Reactivity:
    Cow, Human, Mouse, Pig, Rat
    Host:
    Mouse
    Isotype:
    IgG2a
  • In Stock

    HER-2 / c-erbB-2 / neu / CD340 Antibody [HRB2/258]

    $559.00
    Catalog Number:
    2064-MSM2-CF488-100T
    Gene:
    ERBB2
    Application:
    Flow Cytometry, Immunofluorescence
    Reactivity:
    Human, Rat
    Host:
    Mouse
    Isotype:
    IgG2a
  • In Stock

    Insulin-like Growth Factor-1 (IGF-1) Antibody [SPM406]

    Price range: $259.00 through $559.00
    Catalog Number:
    3479-MSM1X
    Gene:
    IGF1
    Application:
    ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry
    Reactivity:
    Human, Mouse, Rabbit, Rat
    Host:
    Mouse
    Isotype:
    IgG1
  • In Stock

    Insulin-like Growth Factor-1 (IGF-1) Antibody [M23]

    Price range: $259.00 through $559.00
    Catalog Number:
    3479-MSM1
    Gene:
    IGF1
    Application:
    Flow Cytometry, Immunofluorescence
    Reactivity:
    Human, Mouse, Rabbit, Rat
    Host:
    Mouse
    Isotype:
    IgG1
  • In Stock

    Insulin-like Growth Factor-1 (IGF-1) Antibody [IGF1/1020]

    Price range: $259.00 through $559.00
    Catalog Number:
    3479-MSM2
    Gene:
    IGF1
    Application:
    Flow Cytometry, Immunofluorescence
    Reactivity:
    Human, Mouse, Rabbit, Rat
    Host:
    Mouse
    Isotype:
    IgG1
  • In Stock
    Best Seller

    p21WAF1 (Tumor Suppressor Protein) Antibody [WA-1]

    Price range: $259.00 through $559.00
    Catalog Number:
    1026-MSM1
    Gene:
    CDKN1A
    Application:
    Flow Cytometry, Immunofluorescence, Immunohistochemistry
    Reactivity:
    Chimpanzee, Human, Monkey, Mouse, Rat
    Host:
    Mouse
    Isotype:
    IgG1
  • In Stock

    p21WAF1 (Tumor Suppressor Protein) Antibody [HJ21]

    Price range: $259.00 through $559.00
    Catalog Number:
    1026-MSM4
    Gene:
    CDKN1A
    Application:
    Flow Cytometry, Immunofluorescence, Immunohistochemistry
    Reactivity:
    Chimpanzee, Human, Monkey, Mouse, Rat
    Host:
    Mouse
    Isotype:
    IgG1
  • In Stock

    p53 Tumor Suppressor Protein Antibody [PAb240]

    Price range: $259.00 through $559.00
    Catalog Number:
    7157-MSM7
    Gene:
    TP53
    Application:
    ELISA
    Reactivity:
    Cow, Dog, Hamster, Human, Monkey, Mouse, Rat
    Host:
    Mouse
    Isotype:
    IgG1
  • In Stock

    p53 Tumor Suppressor Protein Antibody [PAb122]

    Price range: $259.00 through $559.00
    Catalog Number:
    7157-MSM4
    Gene:
    TP53
    Application:
    ELISA
    Reactivity:
    Dog, Hamster, Human, Monkey, Mouse, Rat
    Host:
    Mouse
    Isotype:
    IgG2b
  • In Stock

    p53 Tumor Suppressor Protein Antibody [SPM349]

    Price range: $259.00 through $559.00
    Catalog Number:
    7157-MSM7X
    Gene:
    TP53
    Application:
    Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
    Reactivity:
    Cow, Dog, Hamster, Human, Monkey, Mouse, Rat
    Host:
    Mouse
    Isotype:
    IgG1
  • In Stock

    Phospho C-Jun (Thr91, Thr93) Antibody [C-J 4C4/1]

    Price range: $259.00 through $559.00
    Catalog Number:
    3725-MSM1
    Gene:
    JUN
    Application:
    Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
    Reactivity:
    Human, Rat
    Host:
    Mouse
    Isotype:
    IgG1
  • Recombinant
    In Stock

    Recombinant Catenin, beta (CTNNB1) Antibody [CTNNB1/2030R]

    Price range: $259.00 through $559.00
    Catalog Number:
    1499-RBM10
    Gene:
    CTNNB1
    Application:
    Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
    Reactivity:
    Guinea Pig, Hamster, Human, Mouse, Rabbit, Rat
    Host:
    Rabbit
    Isotype:
    IgG
  • Recombinant
    In Stock

    Recombinant Catenin, beta (p120) Antibody [rCTNNB1/1507]

    Price range: $259.00 through $559.00
    Catalog Number:
    1499-MSM14
    Gene:
    CTNNB1
    Application:
    ELISA, Flow Cytometry, Immunohistochemistry
    Reactivity:
    Human, Mouse, Rat
    Host:
    Mouse
    Isotype:
    IgG1
  • Recombinant
    In Stock

    Recombinant Catenin, beta (p120) Antibody [rCTNNB1/2173]

    Price range: $259.00 through $559.00
    Catalog Number:
    1499-MSM13
    Gene:
    CTNNB1
    Application:
    Immunofluorescence, Immunohistochemistry, Western Blot
    Reactivity:
    Human, Mouse, Rat
    Host:
    Mouse
    Isotype:
    IgG1
  • Recombinant
    In Stock

    Recombinant Insulin-like Growth Factor-1 (IGF-1) Antibody [IGF1/2872R]

    Price range: $259.00 through $559.00
    Catalog Number:
    3479-RBM3
    Gene:
    IGF1
    Application:
    ELISA, Flow Cytometry, Immunofluorescence
    Reactivity:
    Human, Mouse, Rabbit, Rat
    Host:
    Rabbit
    Isotype:
    IgG
  • Recombinant
    In Stock

    Recombinant p53 Tumor Suppressor Protein Antibody [TP53/3156R]

    Price range: $259.00 through $559.00
    Catalog Number:
    7157-RBM20
    Gene:
    TP53
    Application:
    ELISA, Western Blot
    Reactivity:
    Dog, Hamster, Human, Monkey, Mouse, Rat
    Host:
    Rabbit
    Isotype:
    IgG
  • In Stock

    Catenin, beta (p120) Antibody [12F7]

    Price range: $259.00 through $559.00
    Catalog Number:
    1499-MSM2
    Gene:
    CTNNB1
    Application:
    Flow Cytometry, Immunofluorescence, Western Blot
    Reactivity:
    Human, Mouse, Rat
    Host:
    Mouse
    Isotype:
    IgG1
  • In Stock

    Catenin, beta (p120) Antibody [CTNNB1/1507]

    Price range: $259.00 through $559.00
    Catalog Number:
    1499-MSM7
    Gene:
    CTNNB1
    Application:
    Immunohistochemistry
    Reactivity:
    Human, Mouse, Rat
    Host:
    Mouse
    Isotype:
    IgG1
  • In Stock
    Best Seller

    Catenin, beta (p120) Antibody [CTNNB1/1508]

    Price range: $259.00 through $559.00
    Catalog Number:
    1499-MSM8
    Gene:
    CTNNB1
    Application:
    Immunohistochemistry
    Reactivity:
    Human, Mouse, Rat
    Host:
    Mouse
    Isotype:
    IgG1
  • In Stock

    Catenin, beta (p120) Antibody [CTNNB1/1509]

    Price range: $259.00 through $559.00
    Catalog Number:
    1499-MSM9
    Gene:
    CTNNB1
    Application:
    Immunohistochemistry
    Reactivity:
    Human, Mouse, Rat
    Host:
    Mouse
    Isotype:
    IgG1
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