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Recombinant Mammaglobin (SCGB2A2) (Breast Cancer Marker) Antibody [rMGB/4229]

In Stock
Catalog Number Formulation Size Price
4250-MSM9-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
4250-MSM9-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
4250-MSM9-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
Recombinant Mammaglobin (SCGB2A2) (Breast Cancer Marker) Antibody

Formalin-fixed, paraffin-embedded human breast carcinoma stained with Mammaglobin Recombinant Mouse Monoclonal Antibody (rMGB/4229).

Recombinant Mammaglobin (SCGB2A2) (Breast Cancer Marker) Antibody - Image 2

Formalin-fixed, paraffin-embedded human breast carcinoma stained with Mammaglobin Recombinant Mouse Monoclonal Antibody (rMGB/4229).

Recombinant Mammaglobin (SCGB2A2) (Breast Cancer Marker) Antibody - Image 3

SDS-PAGE Analysis of Purified Mammaglobin Mouse Monoclonal Antibody (rMGB/4229). Confirmation of Integrity and Purity of Antibody.

Mammaglobin Antibody in Western Blot (WB)

Mammaglobin Antibody in Western Blot (WB)

Western Blot Analysis of Human Skin tissue lysate using Mammaglobin Recombinant Mouse Monoclonal Antibody (rMGB/4229).

Mammaglobin Antibody in Western Blot (WB)

Mammaglobin Antibody in Western Blot (WB)

Western Blot Analysis of Skin tissue lysates of different species using Mammaglobin Recombinant Mouse Monoclonal Antibody (rMGB/4229).

Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

Mammaglobin is a 93 amino acid glycoprotein with homology to other secretoglobin-uteroglobin family members. It was originally identified as a breast cancer restricted biomarker by differential screening. Mammaglobin related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin antibody stains cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues.Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.

Product Properties & Targets

Antibody Type
Mouse Monoclonals, Recombinant Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry, Western Blot
Species Reactivity
Human
Isotype / Light Chain
IgG2a / Kappa
Cellular Localization
Secreted
Gene Name
SCGB2A2
Positive Control
HeLa, MCF-7 or T47D cells. Human breast carcinoma. Skin
Immunogen
Stable CHO cell line producing antibody against Mammaglobin.
Alternate Names
Mammaglobin-A, Mammaglobin-1, Secretoglobin family 2A member 2, Mammaglobin-1 (MGB1); Mammaglobin-A; Secretoglobin family 2A member 2 (SCGB2A2); SG2A2; UGB2

Database Links

Entrez Gene ID
4250
SwissProt
Q13296

Additional Information

Clone
rMGB/4229
Chromosome Location
11q12.3
Mol. Weight of Antigen
18kDa
Expression System
CHO Cells
Purification
Protein A

Related Antibodies

View All SCGB2A2 Antibodies

Key References

  • Watson MA., et al.Cancer Res.1999;59:3028 3031.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab produced in the CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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