HSV1 (Herpes Simplex Virus Type I) [HSVI/2095]



The antibody reacts with HSV type 1 specific antigen. It is suitable for detection of HSV in human cellular material obtained from superficial lesions or biopsies and for the early identification of HSV in infected tissue cultures. The herpes simplex virus (HSV) (also known as cold sore, night fever or fever blister) is a virus that causes a contagious disease. There are two main types of Herpes Simplex Virus (HSV), 1 and 2. The HSV-1 strain generally appears in the orafacial organs. HSV2 usually resides in the sacral ganglion at the base of the spine. All herpes viruses are morphologically identical: they have a large double-stranded DNA genome and the virion consists of an icosahedral nucleo-capsid, which is surrounded by a lipid bilayer envelope. UL42, the processivity subunit of the HSV-1DNA polymerase binds DNA as a monomer and is essential for the replication of the virus. UL42 reduces the rate of dissociation from primer-template DNA, but it does not reduce the rate of elongation. UL42 increases the ability of UL9 to load onto DNA, thus increasing its assembly into a functional complex that is capable of unwinding duplex DNA.

Product Properties & Targets

Species Reactivity
Cellular Localization
Gene Name
Mol. Weight of Antigen
Baculovirus-expressed HSV DNA polymerase (POL) and POL/UL42 complex

Database Links

Entrez Gene ID

Additional Information

Human Gene Symbol
Not Applicable
Chromosome Location
Not Applicable

Known Applications & Suggested Dilutions

  • Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes)
  • Optimal dilution for a specific application should be determined.

Key References

  • Nozawa, N., Daikoku, T., Koshizuka, T., Yamauchi, Y., Yoshikawa, T. and Nishiyama, Y. 2003. Subcellular localization of herpes simplex virus type 1 UL51 protein and role of palmitoylation in Golgi apparatus targeting. J Virol. 77: 3204-3216.

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.


This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.


There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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