Formalin-fixed, paraffin-embedded human basal cell carcinoma stained with EpCAM Recombinant Rabbit Monoclonal Antibody (EGP40/2041R).
Formalin-fixed, paraffin-embedded canine (dog) bladder stained with EpCAM Recombinant Rabbit Monoclonal Antibody (EGP40/2041R).
Formalin-fixed, paraffin-embedded feline (cat) small intestine stained with EpCAM Recombinant Rabbit Monoclonal Antibody (EGP40/2041R).
Formalin-fixed, paraffin-embedded human thyroid carcinoma stained with EpCAM Recombinant Rabbit Monoclonal Antibody (EGP40/2041R).
SDS-PAGE Analysis Purified EpCAM Recombinant Rabbit Monoclonal Antibody (EGP40/2041R). Confirmation of Purity and Integrity of Antibody.
Epitope of this MAb is mapped between aa 202-212 of EGP40, which is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. Antibody to Ep-CAM has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.