CDK4 Antibodies

Cyclin-Dependent Kinase 4 (CDK4) has a molecular weight of approximately 34 kDa. It is expressed in various tissues, but its levels fluctuate throughout the cell cycle, peaking during the G1 phase, making it a key regulator of the cell cycle progression. Since aberrant activation or overexpression can contribute to uncontrolled cell division and tumor formation, it is often implicated in cancer.

Antibodies against CDK4 are used in research to study its expression levels in cells and tissues. Immunohistochemistry and western blotting are common techniques employing these antibodies to investigate its presence and regulation in normal and pathological conditions. In a diagnostic context, assessing Cyclin-Dependent Kinase 4 expression levels in tumors may provide information about the aggressiveness of certain cancers and help guide treatment decisions.

Synonyms

Cyclin-dependent kinase 4, CMM3|PSK-J3

Research Areas

Apoptosis, Autophagy, Breast Cancer, Cancer, Cardiovascular, Cell Biology, Cellular Markers and Tags, Developmental Biology, Endocrine, Epigenetics, Gastrointestinal Tract, Hypoxia, Immuno Oncology, Immunology, Kidney, Lymphatic, Metabolism, Microbiology, Muscle, Neuroscience, Pancreatic Cancer, Prostate Cancer, Skin, Stem Cell, AKT Signaling, Angiogenesis, Articular Cartilage Extracellular Matrix, B Cell Markers, Basal Cell Marker, BBB VCAM-1 Signaling, Bladder Cancer, Cardiac Stem Cells, Colon Cancer, Colorectal Cancer, Complement System, CTLA-4 blockade immunotherapy, Cytokine Signaling, Defective Intrinsic Apoptosis, Dendritic Cell Marker, Digestion, Endothelial Cell Marker, Hematopoietic Stem Cells, Immune checkpoint, Infectious Disease, Lipid Metabolism, Lung Cancer, MAPK Signaling, Mast Cell Marker, Melanoma, Mesenchymal Stem Cell Differentiation, Mitochondria Marker, Neural Stem Cells, Neuroinflammation, Nuclear Marker, Oncology, Ovarian Cancer, PD-1 blockade immunotherapy, Signal Transduction, Stem Cell Differentiation, Transcription Factors