Formalin-fixed, paraffin-embedded human Pancreas stained with SOX9 Mouse Monoclonal Antibody (PCRP-SOX9-1A2).
SDS-PAGE Analysis Purified SOX9 Mouse Monoclonal Antibody (PCRP-SOX9-1A2). Confirmation of Purity and Integrity of Antibody.
Analysis of Protein Array containing more than 19,000 full-length human proteins using SOX9 Mouse Monoclonal Antibody (PCRP-SOX9-1A2)
Specificity & Comments
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.