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Home >> Antibodies >> FGF23 (Fibroblast Growth Factor 23)

FGF23 (Fibroblast Growth Factor 23)

Mouse Monoclonal Antibody [Clone FGF23/4169]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
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SDS-PAGE Analysis Purified FGF23Mouse Monoclonal Antibody (FGF23/4169). Confirmation of Purity and Integrity of Antibody.

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IHC analysis of formalin-fixed, paraffin-embedded human kidney stained with FGF23/4169 at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2°: HRP-polymer, 30min. DAB, 5min.

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Analysis of Protein Array containing more than 19,000 full-length human proteins using FGF23-Monospecific Mouse Monoclonal Antibody (FGF23/4169).

Product Details

Synonyms

ADHR; FGF-23; FGFN; Fibroblast growth factor 23; HPDR2; HYPF; Phosphatonin; PHPTC; Tumor-derived hypophosphatemia-inducing factor

Positive Control

Human kidney tissue.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant fragment (around aa25-251) of human FGF23 protein (exact sequence is proprietary)

Cellular Localization

Secreted (extracellular)

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2c, kappa

Mol. Weight of Antigen

12-32kDa

Specificity & Comments

Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10 through FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Yamashita, T., et al. 2000. Biochem. Biophys. Res. Commun. 277: 494-498.

Bioinformatics

  •  Entrez Gene ID: 8074
  •  Gene Symbol: FGF23
  •  SwissProt: Q9GZV9
  •  Chromosome Location: 12p13.32
  •  Unigene: 287370