Formalin-fixed, paraffin-embedded human placenta stained with FABP4 Mouse Monoclonal Antibody (FABP4/4423) at 2ug/ml. Inset: PBS instead of primary antibody, secondary only negative control.
Formalin-fixed, paraffin-embedded human placenta stained with FABP4 Mouse Monoclonal Antibody (FABP4/4423).
Analysis of Protein Array containing more than 19,000 full-length human proteins using FABP4 Mouse Monoclonal Antibody (FABP4/4423).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
Fatty acid-binding proteins, designated FABPs, are a family of homologous, cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). The human A-FABP gene is organized into 4 exons, maps to chromosome 8q21.13, and encodes a 132 amino acid protein. A-FABP protein comprises approximately 1% of the total cytosolic protein in human adipose tissue.