2 Union Square, Union City, CA 94587
contact@NeoBiotechnologies.com
510-376-5603

Home >> Antibodies >> CD8A (Cytotoxic / Suppressor T-Cell Marker)

CD8A (Cytotoxic / Suppressor T-Cell Marker)

Mouse Monoclonal Antibody [Clone RIV11]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
img

SDS-PAGE Analysis Purified CD8A Mouse Monoclonal Antibody (RIV11). Confirmation of Integrity and Purity of Antibody.

Product Details

Synonyms

CD8 antigen, alpha polypeptide (p32), T8/Leu-2 T-lymphocyte differentiation antigen, Ly3, LYT3, MAL, T-cell surface glycoprotein CD8 alpha chain

Positive Control

HuT78 or hPBL. Tonsil.

Known Applications & Suggested Dilutions

Flow Cyt, IF         More Details

Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Human peripheral lymphocytes

Cellular Localization

Cell surface

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

32kDa

Specificity & Comments

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Knapp W. et. al. Leukocyte Typing IV, p342-343, Oxford University Press, 1989
  2. Parnes JR, CD4 and CD8 in T cell lineage commitment: alterations induced by expression of a CD8/CD4 chimeric transgene. Semin Immunol 1994, 6:221-229.
  3. Delon J. et al. CD8 expression allows T cell signaling by monomeric peptide-MHC complexes. Immunity 1998, 9(4):467-73
  4. Akimoto H, et al. Binding of HIV-2 envelope glycoprotein to CD8 molecules and related chemokine production. Immunology 1998, 95(2):214-218
  5. Leahy DJ. A structural view of CD4 and CD8. FASEB J. 1995,9(1):17-25.
  6. Jonker M et al. Side effects and immunogenicity of murine lymphocyte-specific monoclonal antibodies in subhuman primates. Transplantation 1988, 45(4):677-682.

Bioinformatics

  •  Entrez Gene ID: 925
  •  Gene Symbol: CD8A
  •  SwissProt: P01732
  •  Chromosome Location: 2p11.2
  •  Unigene: 85258
NBT00333