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Recombinant FOLH1 / PSMA (Prostate Epithelial Marker) Antibody [FOLH1/13524R]

In Stock
Catalog Number Formulation Size Price
2346-RBM13-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
2346-RBM13-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
2346-RBM13-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression., Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.

Product Properties & Targets

Antibody Type
Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Immunohistochemistry
Species Reactivity
Human
Isotype / Light Chain
IgG / Kappa
Cellular Localization
Cell membrane, Cytoplasm
Gene Name
FOLH1
Positive Control
Highly expressed in prostate epithelium
Immunogen
Recombinant fragment of the human FOLH1 protein (exact sequence is proprietary)
Alternate Names
Glutamate carboxypeptidase 2, FGCP|FOLH|GCP2|GCPII|NAALAD1|PSM|PSMA|mGCP

Database Links

Entrez Gene ID
2346
SwissProt
Q04609

Additional Information

Clone
FOLH1/13524R
Chromosome Location
11p11.12
Mol. Weight of Antigen
84.33kDa
Expression System
CHO Cells
Purification
Protein A

Related Antibodies

View All FOLH1 Antibodies

Functions

  • Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression., Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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