Formalin-fixed, paraffin-embedded human thyroid carcinoma stained with TACSTD2 Recombinant Rabbit Monoclonal Antibody (TACSTD2/6396R).

IHC analysis of formalin-fixed, paraffin-embedded human brain. Negative tissue control using TACSTD2/6396R at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2 °: HRP-polymer, 30min. DAB, 5min.

Formalin-fixed, paraffin-embedded human liver in colon carcinoma stained with TACSTD2 Recombinant Rabbit Monoclonal Antibody (TACSTD2/6396R).

SDS-PAGE Analysis Purified TACSTD2 Recombinant Rabbit Monoclonal (TACSTD2/6396R). Confirmation of Purity and Integrity of Antibody.

Printable Datasheet

TACSTD2 / TROP2 (Epithelial Marker) [TACSTD2/6396R]

Name: TACSTD2 / TROP2 (Epithelial Marker)
SKU: 4070-RBM6
Availability: InStock

Monoclonals Primary Antibodies Rabbit Monoclonals Recombinant Rabbit Monoclonals Recombinants

Summary

TACSTD2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.

Product Properties & Targets

Host

Rabbit

Species Reactivity

Human

Isotype

IgG

Cellular Localization

Membrane

Gene Name

TACSTD2

Mol. Weight of Antigen

40kDa

Immunogen

Recombinant fragment of human TACSTD2 protein (around aa 31-274) (exact sequence is proprietary)

Database Links

Entrez Gene ID

4070

Unigene

23582

SwissProt

P09758

Additional Information

Clone

TACSTD2/6396R

Human Gene Symbol

TACSTD2

Chromosome Location

1p32.1

Known Applications & Suggested Dilutions

Western Blot (1-2ug/ml)
,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 &degC followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Key References

Fornaro, M., et al. 1995. Cloning of the gene encoding Trop-2, a cell-surface glycoprotein expressed by human carcinomas. Int. J. Cancer 62: 610-618.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.