Learn about our comprehensive antibody validation methods to ensure monospecificity.  Antibody Validation>>

Printable Datasheet

Recombinant Ornithine Decarboxylase-1 (ODC-1) Antibody [rODC1/487]

In Stock
Catalog Number Formulation Size Price
4953-MSM6-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
4953-MSM6-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
4953-MSM6-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $60 | Orders outside the US - Contact Us for Order Information | Ships next business day
Western Blot Analysis of PC3 cell lysate using ODC1 Recombinant Mouse Monoclonal Antibody (rODC1/487).

Western Blot Analysis of PC3 cell lysate using ODC1 Recombinant Mouse Monoclonal Antibody (rODC1/487).

SDS-PAGE Analysis Purified ODC1 Recombinant Mouse Monoclonal Antibody (rODC1/487). Confirmation of Purity and Integrity of Antibody

SDS-PAGE Analysis Purified ODC1 Recombinant Mouse Monoclonal Antibody (rODC1/487). Confirmation of Purity and Integrity of Antibody

Applications & Dilutions

Applications Tested Dillution Protocol Note
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Product Properties & Targets

Antibody Type
Mouse Monoclonals, Recombinant Mouse Monoclonals
Host
Mouse
Applications
ELISA, Western Blot
Species Reactivity
Human, Mouse, Rat
Isotype / Light Chain
IgG1 / Kappa
Gene Name
ODC1
Positive Control
PC3 cells.
Immunogen
Recombinant full-length human ODC-1 protein
Alternate Names
Ornithine decarboxylase, Ornithine decarboxylase structural 1; RNODC

Database Links

Entrez Gene ID
4953
SwissProt
P11926

Additional Information

Clone
rODC1/487
Chromosome Location
2p25.1
Mol. Weight of Antigen
53kDa.

Related Antibodies

View All ODC1 Antibodies

Functions

  • Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.

Key References

  • Schipper RG, et al. Preparation and characterization of monoclonal antibodies against ornithine decarboxylase. Journal of Immunological Methods, 1993, 161(2):205-15.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

Reviews

There are no reviews yet.

Be the first to review “Recombinant Ornithine Decarboxylase-1 (ODC-1) Antibody”

Your email address will not be published. Required fields are marked *

PARTNERSHIP OPPORTUNITIES

We hold Exclusive rights to 10,000 recombinant and hybridoma antibody products, available for Licensing or Collaboration.

LETS TALK
NeoBiotechnologies Logo
Company Info
Antibodies
Antibody Validation
Research Areas
Resources
Newsletter Signup Updates & Sales