PARTNERSHIP OPPORTUNITIES
Formalin-fixed, paraffin-embedded human placenta stained with CD147 Mouse Monoclonal Antibody (BSG/7949) at 2ug/ml. Inset: PBS instead of primary antibody; secondary only negative control.
Formalin-fixed, paraffin-embedded human renal cell carcinoma stained with CD147 Mouse Monoclonal Antibody (BSG/7949) at 2ug/ml. HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.
Analysis of Protein Array containing more than 19,000 full-length human proteins using CD147 Mouse Monoclonal Antibody (BSG/7949). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
Western Blot Analysis of HeLa cell lysate using CD147 Mouse Monoclonal Antibody (BSG/7949).
SDS-PAGE Analysis of Purified CD147 Mouse Monoclonal Antibody (BSG/7949). Confirmation of Integrity and Purity of Antibody.
Western Blot Analysis of HepG2, HeLa and MCF7 cell lysates using CD147 Mouse Monoclonal Antibody (BSG/7949).
Western Blot Analysis of Human Brain and Human Heart tissue lysates using CD147 Mouse Monoclonal Antibody (BSG/7949).
Western blot analysis of Human Brain, Mouse Brain, Rat Brain, Hamster Brain, Guinea pig Brain, Rabbit Brain, Human Heart, Mouse Heart, Rat Heart, Hamster Heart, Guinea pig Heart, Rabbit Heart, Human Liver, Mouse Liver, Rat Liver, Hamster Liver, Guinea pig Liver and Rabbit Liver tissue lysates using CD147 Mouse Monoclonal Antibody (BSG/7949).
This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.
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