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Home >> Antibodies >> Lysozyme (Histiocytoma &Monocytic Acute Leukemia Marker)

Lysozyme (Histiocytoma &Monocytic Acute Leukemia Marker)

Mouse Monoclonal Antibody [Clone LYZ/3941]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
img

Formalin-fixed, paraffin-embedded human spleen stained with Lysozyme Mouse Monoclonal Antibody (LYZ/3941). HIER: Tris/EDTA, pH9.0, 45min. 2: HRP-polymer, 30min. DAB, 5min.

img

Formalin-fixed, paraffin-embedded human spleen stained with Lysozyme Mouse Monoclonal Antibody (LYZ/3941). Inset: PBS instead of primary antibody; secondary only negative control.

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Formalin-fixed, paraffin-embedded horse colon stained with Lysozyme Mouse Monoclonal Antibody (LYZ/3941).

img

SDS-PAGE Analysis Purified Lysozyme Mouse Monoclonal Antibody (LYZ/3941). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

1 4 beta N acetlymuramidase C; Lysozyme C; LYZ; LYM; Renal amyloidosis

Positive Control

Human tonsil, spleen, lung or kidney.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant fragment of human Lysozyme protein (around aa 18-147) (exact sequence is proprietary)

Cellular Localization

Secreted.

Species Reactivity

Human. Horse.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

17kDa

Specificity & Comments

Lysozyme is an enzyme, commonly referred to as the body s own antibiotic since it kills bacteria.Natural substrate of lysozyme is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the antimicrobial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. The protein has antibacterial activity against a number of bacterial species.Lysozyme is synthesized predominantly in reactive histiocytes rather than in resting, unstimulated phagocytes. This antibody labels myeloid cells, histiocytes, granulocytes, macrophages and monocytes. It is helpful in the identification of myeloid or monocytic nature of acute leukemia.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Canfield, R.E., et al. 1971. Primary structure of lysozymes from man andgoose. Nat. New Biol. 232: 16-17.

Bioinformatics

  •  Entrez Gene ID: 4069
  •  Gene Symbol: LYZ
  •  SwissProt: P61626
  •  Chromosome Location: 12q15
  •  Unigene: 524579