Formalin-fixed, paraffin-embedded human Tonsil stained with IL3RA / CD123 Rabbit Recombinant Monoclonal Antibody (IL3RA/2947R).
SDS-PAGE Analysis Purified IL3RA Rabbit Recombinant Monoclonal Antibody (IL3RA/2947R). Confirmation of Integrity and Purity of Antibody.
Analysis of Protein Array containing more than 19,000 full-length human proteins using IL3RA / CD123 Rabbit Recombinant Monoclonal Antibody (IL3RA /2947R).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.