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Home >> Antibodies >> GM-CSF (Granulocyte/Macrophage - Colony Stimulating Factor)

GM-CSF (Granulocyte/Macrophage - Colony Stimulating Factor)

Rat Monoclonal Antibody [Clone SPM469]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00

Product Details

Synonyms

Burst Promoting Activity; Colony stimulating factor 2 (granulocyte-macrophage); Eosinophil Colony Stimulating Factor; Granulocyte Macrophage Colony Stimulating Factor; Molgramostin; Pluripoietin Alpha; Sargramostim

Positive Control

Lymph node and tonsil.

Known Applications & Suggested Dilutions

Neut. Studies, Flow Cyt, IF         More Details

Neutralization Studies (Order Ab without Azide)
Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human GM-CSF protein

Cellular Localization

Secreted (extracellular)

Species Reactivity

Human. Cynomolgus. Rhesus Monkey.

Host / Ig Isotype

Rat / IgG2a, kappa

Mol. Weight of Antigen

22kDa

Specificity & Comments

Granulocyte/macrophage - Colony-stimulating factor (GM-CSF) is a hematopoietic factor that is produced by activated T-cells, B-cells, mast cells, macrophages, fibroblasts, and endothelial cells. In addition to supporting colony formation of granulocyte/macrophage progenitors, GM-CSF is a growth factor for erythroid, megakaryocyte, and eosinophil progenitors.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Abrams J, et al. 1992. Immunol. Rev. 127:5.
  2. Abrams J, et al. 1994. Eosinophils in Allergy and Inflammation. Marcel Dekker New York. p.133.
  3. Bacchetta R, et al. 1990. J. Immunol. 144:902.
  4. Kita H, et al. 1991. J. Exp. Med. 174:745.
  5. Andersson J, et al. 1994. Immunology 83:16.
  6. Andersson U, et al. 1999. Detection and quantification of gene expression. New York:Springer-Verlag.

Bioinformatics

  •  Entrez Gene ID: 1437
  •  Gene Symbol: CSF2
  •  SwissProt: P04141
  •  Chromosome Location: 5q31.1
  •  Unigene: 1349
NBT00662