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GM-CSF (Granulocyte/Macrophage – Colony Stimulating Factor) Antibody [SPM469]

In Stock
Catalog Number Formulation Size Price
1437-RTM1X-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
1437-RTM1X-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
1437-RTM1X-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $60 | Orders outside the US - Contact Us for Order Information | Ships next business day

Applications & Dilutions

Applications Tested Dillution Protocol
Flow Cytometry (Flow)
1-2ug/million cells
Immunofluorescence (IF)
1-3ug/ml

Summary

Granulocyte/macrophage – Colony-stimulating factor (GM-CSF) is a hematopoietic factor that is produced by activated T-cells, B-cells, mast cells, macrophages, fibroblasts, and endothelial cells. In addition to supporting colony formation of granulocyte/macrophage progenitors, GM-CSF is a growth factor for erythroid, megakaryocyte, and eosinophil progenitors.

Product Properties & Targets

Antibody Type
Host
Rat
Species Reactivity
Isotype / Light Chain
IgG2a / Kappa
Cellular Localization
Secreted
Gene Name
Positive Control
Lymph node and tonsil.
Immunogen
Recombinant human GM-CSF protein
Alternate Names
Granulocyte-macrophage colony-stimulating factor, Colony-stimulating factor, Molgramostin, Sargramostim, Burst Promoting Activity; Colony stimulating factor 2 (granulocyte-macrophage); Eosinophil Colony Stimulating Factor; Granulocyte Macrophage Colony Stimulating Factor; Molgramostin; Pluripoietin Alpha; Sargramostim

Database Links

Entrez Gene ID
SwissProt

Additional Information

Clone
SPM469
Chromosome Location
5q31.1
Mol. Weight of Antigen
22kDa

Functions

  • Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.

Key References

  • Abrams J, et al. 1992. Immunol. Rev. 127:5.
  • Abrams J, et al. 1994. Eosinophils in Allergy and Inflammation. Marcel Dekker New York. p.133.
  • Bacchetta R, et al. 1990. J. Immunol. 144:902.
  • Kita H, et al. 1991. J. Exp. Med. 174:745.
  • Andersson J, et al. 1994. Immunology 83:16.
  • Andersson U, et al. 1999. Detection and quantification of gene expression. New York:Springer-Verlag.

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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