
SDS-PAGE Analysis of Purified Aciculin Rabbit Monoclonal Antibody (PGM5/7005R). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human tonsil prostate with Aciculin Rabbit Monoclonal Antibody (PGM5/7005R) at 2ug/ml. HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.

Western Blot Analysis of Human Kidney, Human Skeletal muscle and PC3 lysates using Aciculin Recombinant Rabbit Monoclonal Antibody (PGM5/7005R).
Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that belongs to the phosphoglucomutase family of phosphotransferases, which play an important role in the interconversion of glucose-1-phosphate and glucose-6-phosphate. Localized to the cell junction and expressed at high levels in smooth and cardiac muscle, Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, possibly playing a role in cytoskeletal organization and function. Aciculin exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome.
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