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Home >> Antibodies >> Aciculin / Phosphoglucomutase 5 (PGM5)

Aciculin / Phosphoglucomutase 5 (PGM5)

Recombinant Rabbit Monoclonal Antibody [Clone PGM5/7005R]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
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SDS-PAGE Analysis Purified Aciculin Rabbit Monoclonal Antibody (PGM5/7005R). Confirmation of Purity and Integrity of Antibody.

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Formalin-fixed, paraffin-embedded human tonsil prostate with Aciculin Rabbit Monoclonal Antibody (PGM5/7005R) at 2ug/ml. HIER: Tris/EDTA, pH9.0, 45min. 2: HRP-polymer, 30min. DAB, 5min.

Product Details

Synonyms

Aciculin; PGM-RP; PGM5; PGMRP; phosphoglucomutase 5; Phosphoglucomutase-like protein 5; Phosphoglucomutase-related protein

Positive Control

Human heart muscle or smooth muscle (IHC). Mouse heart tissue lysate (WB).

Known Applications & Suggested Dilutions

ELISA, IF, Western Blot         More Details

ELISA (For coating, order antibody without BSA)
Immunofluorescence (1-2ug/ml)
Western Blot (1-2ug/ml),Immunohistochemistry (Formalin-fixed) (2-4ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Cytoskeletal fraction of the human myometrium tissue extract

Cellular Localization

Cytoplasm.

Species Reactivity

Human.

Host / Ig Isotype

Rabbit / IgG, kappa

Mol. Weight of Antigen

56kDa

Specificity & Comments

Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that belongs to the phosphoglucomutase family of phosphotransferases, which play an important role in the interconversion of glucose-1-phosphate and glucose-6-phosphate. Localized to the cell junction and expressed at high levels in smooth and cardiac muscle, Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, possibly playing a role in cytoskeletal organization and function. Aciculin exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Belkin, A.M. and Burridge, K. 1994. Expression and localization of the phosphoglucomutase-related cytoskeletal protein, Aciculin, in skeletal muscle. J. Cell Sci. 107: 1993-2003.

Bioinformatics

  •  Entrez Gene ID: 5239
  •  Gene Symbol: PGM5
  •  SwissProt: Q15124
  •  Chromosome Location: 9q21.11
  •  Unigene: 307835