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ZXDC Antibody [PCRP-ZXDC-2B5]

In Stock
Catalog Number Formulation Size Price
79364-MSM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$249.00
79364-MSM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$539.00
79364-MSM2-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$539.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day

Applications & Dilutions

Applications Tested Dillution Protocol Note
Flow Cytometry (Flow)
1-2ug/million cells
Immunofluorescence (IF)
1-3ug/ml
Immunohistochemistry (IHC)
1-2ug/ml
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

Enables C2H2 zinc finger domain binding activity; LRR domain binding activity; and transcription coactivator activity. Involved in positive regulation of transcription, DNA-templated. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. �

Product Properties & Targets

Antibody Type
Host
Mouse
Species Reactivity
Research Areas
Isotype / Light Chain
IgG1 /
Cellular Localization
Nucleus.
Gene Name
Positive Control
HeLa cells.
Immunogen
Recombinant full-length human ZXDC protein
Alternate Names
Zinc finger protein ZXDC, ZXD-like zinc finger protein, FLJ13861, MGC11349

Database Links

Entrez Gene ID
SwissProt

Additional Information

Clone
PCRP-ZXDC-2B5
Chromosome Location
3q21.3
Mol. Weight of Antigen
90kDa

Functions

  • Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.

Key References

  • Blackshaw S, et al. Nature methods15.5 (2018 May): 330-338.
  • Statement for PublicationAll investigators should include an acknowledgment in the publications the benefit from the use of this product. Suggested statement: PCRP-ZXDC-2B5 was developed by JHU/CDI under Protein Capture Reagents Program of NICHD of the NIH.

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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