ZNF690 / ZSCAN29 [ZSCAN29/2610]

Clear

Summary

Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 690 (ZNF690), also known as ZSCAN29, is a 851 amino acid member of the Kruppel C2H2- type zinc finger protein family. Localized to the nucleus, ZNF690 contains six C2H2-type zinc fingers and one KRAB domain through which it is thought to be involved in DNA-binding and transcriptional regulation. Four isoforms of ZNF690 exist as a result of alternative splicing events.

Product Properties & Targets

Host
Species Reactivity
Isotype
Cellular Localization
Nucleus
Light Chain
Gene Name
Positive Control
HeLa whole cell lysate. Tonsil. Breast Carcinoma.
Immunogen
Recombinant full-length human ZSCAN29 protein
Alternate Names
Zinc finger and SCAN domain-containing protein 29, Zinc finger protein 690, FLJ35867; KOX31 like zinc finger protein; MGC129894; MGC129895; zinc finger and SCAN domain-containing 29 (ZSCAN29); Zinc finger protein 690 (ZNF690)

Database Links

Entrez Gene ID
Unigene
SwissProt

Additional Information

Clone
ZSCAN29/2610
Human Gene Symbol
ZSCAN29
Chromosome Location
15q15.3
Mol. Weight of Antigen
97kDa

Functions

  • May be involved in transcriptional regulation.

Known Applications & Suggested Dilutions

  • ELISA (For coating, order antibody without BSA)
  • Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes)
  • Optimal dilution for a specific application should be determined.

Key References

  • Thiesen, H.J. 1990. New Biol. 2: 363-374.

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

Reviews

There are no reviews yet.

Be the first to review “ZNF690 / ZSCAN29”

Your email address will not be published. Required fields are marked *

Recombinant mouse monoclonal antibodies and recombinant rabbit monoclonals to support your research

Shop Primary Antibodies