Formalin-fixed, paraffin-embedded human Pancreas stained with Synaptophysin-Monospecific Mouse Monoclonal Antibody (SYP/3551).
Formalin-fixed, paraffin-embedded human Pancreatic Carcinoma stained with Synaptophysin-Monospecific Mouse Monoclonal Antibody (SYP/3551).
SDS-PAGE Analysis Purified Synaptophysin Mouse Monoclonal Antibody (SYP/3551). Confirmation of Purity and Integrity of Antibody.
Analysis of Protein Array containing more than 19,000 full-length human proteins using Synaptophysin-Monospecific Mouse Monoclonal Antibody (SYP/3551).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
This Monospecific monoclonal antibody recognizes a protein of 38kDa that is identified as synaptophysin. It is an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.