Western Blot Analysis of PANC-1 cell lysate using Spectrin beta III Rabbit Recombinant Monoclonal (SPTBN2/2887R).
SDS-PAGE Analysis Purified Spectrin beta III Rabbit Recombinant Monoclonal (SPTBN2/2887R). Confirmation of Purity and Integrity of Antibody.
Immunofluorescence Analysis of Human HeLa cells labeling SPTBN2 with Spectrin beta III Rabbit Recombinant Monoclonal (SPTBN2/2887R) followed by Goat anti-mouse IgG-CF488 (Green). The nuclear counterstain is Reddot (Red).
Flow Cytometric Analysis of HeLa cells using Spectrin beta III Rabbit Recombinant Monoclonal Antibody (SPTBN2/2887R) followed by Goat anti-rabbit IgG-CF488 (Blue); Isotype Control (Red).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II) four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites.