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Home >> Antibodies >> PAX7 (Rhabdomyosarcoma Marker)

PAX7 (Rhabdomyosarcoma Marker)

Mouse Monoclonal Antibody [Clone PAX7/497]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
459.00
459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
459.00
459.00
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Western Blot of HeLa cell lysate using PAX7 Mouse Monoclonal Antibody (PAX7/497).

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SDS-PAGE Analysis Purified PAX7 Mouse Monoclonal Antibody (PAX7/497).

Product Details

Synonyms

HUP1; Paired box gene 7; Paired box homeotic gene 7; Paired domain gene HuP1; PAX7 transcriptional factor; PAX7/FKHR fusion gene; PAX7B; RMS2

Positive Control

HeLa, Jurkat, A431, MCF-7, U2OS or NIH/3T3 cells. Rhabdomyosarcoma (RMS).

Known Applications & Suggested Dilutions

IF, Flow Cyt, Western Blot         More Details

Immunofluorescence (1-2ug/ml)
Flow Cytometry (1-2ug/million cells)
Western Blot (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant fragment (aa301-505) of human PAX7 protein (exact sequence is proprietary)

Cellular Localization

Nuclear

Species Reactivity

Human. Mouse. Rat Chicken. Zebrafish.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

57kDa

Specificity & Comments

The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

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200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bioinformatics

  •  Entrez Gene ID: 5081
  •  Gene Symbol: PAX7
  •  SwissProt: P23759
  •  Chromosome Location: 1p36.13
  •  Unigene: 113253
NBT00497