Home >> Antibodies >> PAX5 / BSAP (Early B-Cell Marker)

PAX5 / BSAP (Early B-Cell Marker)

Recombinant Mouse Monoclonal Antibody [Clone rPAX5/4228]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

Formalin-fixed, paraffin-embedded human tonsil stained with PAX5 Recombinant Mouse Monoclonal Antibody (rPAX5/4228).

Formalin-fixed, paraffin-embedded human tonsil stained with PAX5 Recombinant Mouse Monoclonal Antibody (rPAX5/4228).

SDS-PAGE Analysis Purified PAX5 Recombinant Mouse Monoclonal Antibody (rPAX5/4228). Confirmation of Purity and Integrity.

Formalin-fixed, paraffin-embedded human tonsil stained with PAX5 Recombinant Mouse Monoclonal Antibody (rPAX5/4228).

SDS-PAGE Analysis Purified PAX5 Recombinant Mouse Monoclonal Antibody (rPAX5/4228). Confirmation of Purity and Integrity.

Product Details

Synonyms

B cell lineage specific activator; BSAP; EBB-1; KLP; Paired box 5

Positive Control

Raji, DAUDI or Ramos cells. Human tonsil, spleen or lymph node.

Known Applications & Suggested Dilutions

IHC-P More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

A recombinant fragment (around aa 235-382) of human PAX5 protein (exact sequence is proprietary)

Cellular Localization

Nuclear

Species Reactivity

Human. Dog

Host / Ig Isotype

Mouse / IgG2a, kappa

Mol. Weight of Antigen

42kDa

Specificity & Comments

The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis; therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.