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Home >> Antibodies >> FSH-beta (Follicle Stimulating Hormone-beta)

FSH-beta (Follicle Stimulating Hormone-beta)

Mouse Monoclonal Antibody [Clone FSHb/1062]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
img

Formalin-fixed, paraffin-embedded human Pituitary stained with FSH beta Mouse Monoclonal Antibody (FSHb/1062).

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SDS-PAGE Analysis Purified FSH beta Mouse Monoclonal Antibody (FSHb/1062). Confirmation of Integrity and Purity of Antibody.

Product Details

Synonyms

Follicle stimulating hormone beta polypeptide; Follicle stimulating hormone beta subunit; Follitropin beta chain; Follitropin subunit beta; FSH-B; FSH-beta; FSHB; FSHbeta

Positive Control

Anterior Pituitary.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (0.1-0.2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length hFSH beta sub-unit

Cellular Localization

Cytoplasmic, secreted

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

22kDa

Specificity & Comments

This MAb reacts with a protein of 22kDa, identified as beta sub-unit of FSH. It does not cross react with the alpha sub-unit. Follicle stimulating hormone (FSH) is a hormone synthesized and secreted by gonadotrophs in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Schmidt M et al. Pathol Res Pract. 2001;197(10):663-9
  2. La Rosa S et al. Virchows Arch. 2000 Sep;437(3):264-9
  3. Zheng W et al. Gynecol Oncol. 2000 jan;76(1):80-8

Bioinformatics

  •  Entrez Gene ID: 2488
  •  Gene Symbol: FSHB
  •  SwissProt: P01225
  •  Chromosome Location: 11p13
  •  Unigene: 36975
NBT01062