Western Blot Analysis of human HeLa cell lysate using Ferritin, Light Chain Mouse Monoclonal Antibody (FTL/1389).
SDS-PAGE Analysis Purified Ferritin, Light Chain Mouse Monoclonal Antibody (FTL/1389). Confirmation of Integrity and Purity of Antibody
Analysis of Protein Array containing more than 19,000 full-length human proteins using Ferritin, Light Chain Mouse Monoclonal Antibody (FTL/1389)
Western Blot Analysis of kidney tissue lysate using Ferritin, Light Chain Monoclonal Antibody (FTL/1389).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.