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FABP5 (Marker of Metastatic Potential in Colorectal Cancer)

Recombinant Rabbit Monoclonal Antibody [Clone FABP5/6353R]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

Formalin-fixed, paraffin-embedded human liver metastasized to colon stained with FABP5 Recombinant Rabbit Monoclonal Antibody (FABP5/6353R).

Formalin-fixed, paraffin-embedded human prostate carcinoma stained with FABP5 Recombinant Rabbit Monoclonal Antibody (FABP5/6353R).

Western blot analysis of HeLa cell lysate using FABP5 Recombinant Rabbit Monoclonal Antibody (FABP5/6353R).

Western blot analysis of Raji cell lysate using FABP5 Recombinant Rabbit Monoclonal Antibody (FABP5/6353R).

Formalin-fixed, paraffin-embedded human liver metastasized to colon stained with FABP5 Recombinant Rabbit Monoclonal Antibody (FABP5/6353R).

Formalin-fixed, paraffin-embedded human prostate carcinoma stained with FABP5 Recombinant Rabbit Monoclonal Antibody (FABP5/6353R).

Western blot analysis of HeLa cell lysate using FABP5 Recombinant Rabbit Monoclonal Antibody (FABP5/6353R).

Western blot analysis of Raji cell lysate using FABP5 Recombinant Rabbit Monoclonal Antibody (FABP5/6353R).

Product Details

Synonyms

FABP5; E-FABP; EFABP; PA-FABP; PAFABP

Positive Control

MOLT-4, HeLa or HEK-293 cells. Keratinocytes; highly expressed in psoriatic skin.

Known Applications & Suggested Dilutions

IF, Western Blot, IHC-P More Details

Immunofluorescence (1-2ug/ml)
Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human full-length FABP5 protein

Cellular Localization

Nuclear. Cytoplasmic.

Species Reactivity

Human.

Host / Ig Isotype

Rabbit / IgG

Mol. Weight of Antigen

15.4kDa

Specificity & Comments

This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. FABP5 is also associated with poor survival in triple-negative breast cancer. Additionally, FABP5 gene is upregulated in colorectal cancer cells compared to normal colon cells in a manner that correlates with disease stage and that FABP5 significantly promotes colorectal cancer cell growth and metastatic potential.