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Home >> Antibodies >> EZH2 / KMT6

EZH2 / KMT6

Mouse Monoclonal Antibody [Clone EZH2/2536]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
459.00
459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
459.00
459.00
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SDS-PAGE Analysis Purified EZH2 / KMT6 Mouse Monoclonal Antibody (EZH2/2536). Confirmation of Purity and Integrity of Antibody.

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Western Blot Analysis of MCF-7 cell lysate using EZH2 / KMT6 Mouse Monoclonal Antibody (EZH2/2536).

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Analysis of Protein Array containing more than 19,000 full-length human proteins using EZH2 Mouse Monoclonal Antibody (EZH2/2536).

Product Details

Synonyms

Enhancer of zeste 2 polycomb repressive complex 2 subunit; Enhancer of zeste homolog 2 (EZH2); ENX1; Enx1h; EZH2b; Histone-lysine N-methyltransferase EZH2; KMT6; KMT6A; Lysine N-methyltransferase 6; WVS; WVS2

Positive Control

MCF7, HeLa, U-2 OS or HEK-293 whole cell lysates. Human tonsil, testis or prostate tissue.

Known Applications & Suggested Dilutions

Western Blot         More Details

Western Blot (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human EZH2 protein

Cellular Localization

Nucleus.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2a, kappa

Mol. Weight of Antigen

81-102kDa

Specificity & Comments

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Yamagishi M et al. Curr Opin Oncol. 2017 Sep;29(5):375-381.
  2. Han Li C et. al. Curr Protein Pept Sci. 2015;16(6):559-70.
  3. Shinozaki-Ushiku, A. et al. Histopathology 2017; 70, 722-733.

Bioinformatics

  •  Entrez Gene ID: 2146
  •  Gene Symbol: EZH2
  •  SwissProt: Q15910
  •  Chromosome Location: 7q36.1
  •  Unigene: 444082
NBT02536