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Formalin-fixed, paraffin-embedded human tonsil stained with EZH2 / KMT6 Mouse Monoclonal Antibody (EZH2/6991). Inset: PBS instead of primary antibody; secondary only negative control.
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.
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