Home >> Antibodies >> DAZL (Deleted in Azoospermia-like)

DAZL (Deleted in Azoospermia-like)

Mouse Monoclonal Antibody [Clone DAZL/4253]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

SDS-PAGE Analysis Purified DAZL Mouse Monoclonal Antibody (DAZL/4253) Confirmation of Integrity and Purity of Antibody.

Western blot Analysis testis tissue lysate using DAZL Mouse Monoclonal Antibody (DAZL/4253).

Formalin-fixed, paraffin-embedded human testis stained with DAZL Mouse Monoclonal Antibody (DAZL/4253).

SDS-PAGE Analysis Purified DAZL Mouse Monoclonal Antibody (DAZL/4253) Confirmation of Integrity and Purity of Antibody.

Western blot Analysis testis tissue lysate using DAZL Mouse Monoclonal Antibody (DAZL/4253).

Formalin-fixed, paraffin-embedded human testis stained with DAZL Mouse Monoclonal Antibody (DAZL/4253).

Product Details

Synonyms

Deleted in azoospermia-like, DAZL, DAZ homolog, DAZ-like autosomal, Deleted in azoospermia-like 1, SPGY-like-autosomal, DAZH, DAZL1, DAZLA, SPGYLA

Positive Control

Human testis or ovary tissue.

Known Applications & Suggested Dilutions

IF, Western Blot, IHC-P More Details

Immunofluorescence (1-2ug/ml)
Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recognizes DAZL protein C terminus sequence CRVHHFRRSRAMLKSV.

Cellular Localization

Cytoplasmic

Species Reactivity

Human, Mouse, Rat and Cynomolgus monkey.

Host / Ig Isotype

Mouse / IgG1

Mol. Weight of Antigen

33kDa

Specificity & Comments

Specific for human DAZL, a member of the DAZ (deleted in azoospermia) family of RNA binding proteins. DAZL is expressed in fetal and adult testes and ovaries, and is believed to play a role in germ cell development. In adult germ cells, the expression of DAZL is localized to the cytoplasm. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Clone DAZL/4253 recognizes DAZL at its C terminus, and is used in detection of DAZL expression by various methods.